Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915212 | 0.83 | KDM4E (0.43) | KDM4EHPGDLMNAHTTALDH1A1 | |
| SCHEMBL8918377 | 0.80 | SIGMAR1 (0.42) | KDM4EHPGDLMNAHTTALDH1A1 | |
| SCHEMBL9213950 | 0.79 | PDE10A (0.41) | KDM4EHPGDLMNAALDH1A1RAB9A | |
| SCHEMBL8017018 | 0.76 | PDE10A (0.45) | KDM4EHPGDLMNAALDH1A1RAB9A | |
| SCHEMBL8915877 | 0.76 | POLB (0.47) | KDM4EHPGDLMNAPKMHTT | |
| SCHEMBL8914183 | 0.74 | GAA (0.50) | KDM4EHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL8916464 | 0.74 | DRD3 (0.43) | ALDH1A1MEN1KMT2AATMSIGMAR1 | |
| SCHEMBL9052359 | 0.73 | GRIN2B (0.43) | KDM4EHPGDLMNAALDH1A1RAB9A | |
| SCHEMBL8914024 | 0.72 | L3MBTL1 (0.45) | KDM4EHPGDALDH1A1TP53MAPT | |
| SCHEMBL8008533 | 0.72 | ALDH1A1 (0.53) | KDM4EHPGDLMNAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |