Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914910 | 0.84 | ALOX15 (0.39) | DRD3KMT2AMEN1HRH3ALDH1A1 | |
| SCHEMBL8915212 | 0.83 | KDM4E (0.43) | SIGMAR1ALDH1A1POLB | |
| SCHEMBL8915844 | 0.78 | RAB9A (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8915877 | 0.76 | POLB (0.47) | THRBHRH3SIGMAR1ALDH1A1POLB | |
| SCHEMBL8914425 | 0.75 | ALDH1A1 (0.52) | DRD3KMT2AMEN1ALDH1A1HTR7 | |
| SCHEMBL7005383 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL8918345 | 0.73 | MTNR1A (0.49) | KMT2AALDH1A1 | |
| SCHEMBL8914311 | 0.72 | ALOX15 (0.39) | DRD3ALDH1A1POLB | |
| SCHEMBL7011575 | 0.71 | CA2 (0.34) | ALDH1A1 | |
| SCHEMBL8916499 | 0.71 | DRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |