Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914577 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1LMNATP53MAPK1 | |
| SCHEMBL8915212 | 0.76 | KDM4E (0.43) | PDE10AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL8918377 | 0.76 | SIGMAR1 (0.42) | PDE10AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL9213950 | 0.75 | PDE10A (0.41) | PDE10AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL8915606 | 0.73 | RAB9A (0.69) | PDE10AALDH1A1RAB9AHPGDHSD17B10 | |
| SCHEMBL8916044 | 0.73 | USP2 (0.49) | PDE10AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL8914486 | 0.71 | KDM4E (0.49) | PDE10AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL8914024 | 0.70 | L3MBTL1 (0.45) | PDE10AKDM4EALDH1A1TP53HPGD | |
| SCHEMBL8914183 | 0.70 | GAA (0.50) | PDE10AKDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL8915877 | 0.70 | POLB (0.47) | KDM4EALDH1A1LMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000212180-A | QUINOLINE COMPOUND | WELFIDE CORP | 2000-08-02 | — | — | JP | disclosed |