SCHEMBL891492

SCHEMBL891492

c1ccc(Oc2ccc(OCc3ccccc3COc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.59
PTPRC P08575 1/20 0.56
PTPN1 P18031 1/20 0.56
PLA2G2A P14555 1/20 0.55
TSHR P16473 1/20 0.55
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
F2 P00734 1/20 0.53
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
TMPRSS6 Q8IU80 1/20 0.53
ST14 Q9Y5Y6 1/20 0.53
KDM4E B2RXH2 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
FFAR1 O14842 3/20 0.51
FFAR4 Q5NUL3 1/20 0.50
MAOA P21397 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931875 0.91 PTPRC (0.59) PTPRCPTPN1F2PRSS1PRSS2
SCHEMBL11854894 0.90 LTA4H (0.60) LTA4HPTPRCPTPN1PLA2G2ANR1H2
SCHEMBL11860320 0.86 MAOB (0.61) LTA4HPLA2G2AKDM4EFFAR1FFAR4
SCHEMBL11849613 0.86 NR4A2 (0.66) LTA4HPTPN1PLA2G2AMAOA
SCHEMBL28044355 0.83 FFAR1 (0.65) LTA4HPTPRCPTPN1TSHRKDM4E
SCHEMBL11849334 0.82 LMNA (0.69) LTA4HSMN1; SMN2FFAR1FFAR4MAOA
SCHEMBL891493 0.82 FFAR1 (0.69) LTA4HSMN1; SMN2FFAR1FFAR4MAOA
SCHEMBL10918547 0.80 SMN1; SMN2 (0.50) PTPRCPTPN1F2PRSS1PRSS2
SCHEMBL110991 0.80 SMN1; SMN2 (0.74) PTPRCPTPN1F2PRSS1PRSS2
SCHEMBL695715 0.80 SMN1; SMN2 (0.50) PTPRCPTPN1F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722574-B2 Thermal imaging members and methods ZINK IMAGING, INC. (US) 2014-05-13 US claimed
US-20130059726-A1 THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2013-03-07 US claimed
US-7807607-B2 Color-forming compounds and use thereof in imaging members and methods ZINK IMAGING, INC. (US) 2010-10-05 US claimed
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO claimed
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2009-05-28 US claimed
EP-2461984-B1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME ZINK IMAGING INC (US) 2016-05-04 EP disclosed
EP-2485900-B1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING INC (US) 2014-05-21 EP disclosed
US-20130303670-A1 COMPOSITIONS, THERMALLY-INSULATING LAYERS, AND DIRECT THERMALLY IMAGING MEMBERS CONTAINING THE SAME ZINK IMAGING INC (US) 2013-11-14 US disclosed
US-8377844-B2 Thermally-insulating layers and direct thermal imaging members containing same ZINK IMAGING, INC. (US) 2013-02-19 US disclosed
US-8372782-B2 Imaging system ZINK IMAGING, INC. (US) 2013-02-12 US disclosed
EP-2485900-A1 MULTICOLOUR THERMAL IMAGING MATERIAL Zink Imaging, Inc. (US) 2012-08-15 EP disclosed
EP-2461984-A1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME Zink Imaging, Inc. (US) 2012-06-13 EP disclosed
US-20110098487-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2011-04-28 US disclosed
WO-2011044049-A1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING, INC. (US) 2011-04-14 WO disclosed
WO-2011017184-A1 THERMALLY-INSULATING LAYERS AND DIRECT THERMAL IMAGING MEMBERS CONTAINING SAME ZINK IMAGING, INC. (US) 2011-02-10 WO disclosed
US-7807607-B2 Color-forming compounds and use thereof in imaging members and methods ZINK IMAGING, INC. (US) 2010-10-05 US disclosed
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO disclosed
US-20100099556-A1 Imaging System ZINK IMAGING, INC. 2010-04-22 US disclosed
US-20100087316-A1 Thermally-Insulating Layers and Direct Thermal Imaging Members Containing Same ZINK HOLDINGS LLC 2010-04-08 US disclosed
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098487-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS HCCS, RB1, CACYBP LTA4H 2979/4885PTPRC 3758/4885PTPN1 4555/4885
US-20130059726-A1 THERMAL IMAGING MEMBERS AND METHODS HEATR1, HEATR6, HSPBP1 LTA4H 3239/4885PTPRC 4121/4885PTPN1 4646/4885
US-20090137389-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS HCCS, RB1, CACYBP LTA4H 2979/4885PTPRC 3758/4885PTPN1 4555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.