Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109933 | 0.77 | ALDH1A1 (0.44) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL891571 | 0.77 | KDM4E (0.39) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5582429 | 0.76 | KDM4E (0.42) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9725229 | 0.75 | KDM4E (0.41) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL2974731 | 0.74 | MAPT (0.37) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL8617028 | 0.73 | KDM4E (0.55) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL12403375 | 0.70 | KDM4E (0.51) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL7257009 | 0.70 | L3MBTL1 (0.36) | KDM4EL3MBTL1TSHRALDH1A1MAPK1 | |
| SCHEMBL28958670 | 0.69 | CYP3A4 (0.54) | KDM4EL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL22354569 | 0.69 | KDM4E (0.73) | KDM4EL3MBTL1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632051-B2 | Hair bleaching agent and method for gentle oxidative lightening of hair | HENKEL AG & CO. KGAA (DE) | 2020-04-28 | — | — | US | disclosed |
| US-20190175462-A1 | HAIR BLEACHING AGENT AND METHOD FOR GENTLE OXIDATIVE LIGHTENING OF HAIR | HENKEL AG & CO. KGAA (DE) | 2019-06-13 | — | — | US | disclosed |
| US-10143634-B2 | Thickening developer for oxidation dyes | HENKEL AG & CO. KGAA (DE) | 2018-12-04 | — | — | US | disclosed |
| US-20170273879-A1 | THICKENING DEVELOPER FOR OXIDATION DYES | HENKEL AG & CO. KGAA (DE) | 2017-09-28 | — | — | US | disclosed |
| US-20170252280-A1 | METHOD FOR SIMULTANEOUSLY AND PERMANENTLY RESHAPING AND COLORING KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2017-09-07 | — | — | US | disclosed |
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-8790417-B2 | Gentle hair color pretreatment with silicone and oily oxidants | HENKEL AG & CO. KGAA (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8784507-B2 | Post oxidative hair treatment agent with silicone | HENKEL AG & CO. KGAA (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20140170223-A1 | POST OXIDATIVE HAIR TREATMENT AGENT WITH SILICONE | HENKEL AG & CO. KGAA (DE) | 2014-06-19 | — | — | US | disclosed |
| US-20140165300-A1 | REDUCTION OF AMMONIA ODOR WHEN COLORING AND/OR LIGHTENING HAIR | HENKEL AG & CO. KGAA (DE) | 2014-06-19 | — | — | US | disclosed |
| US-20140165303-A1 | GENTLE HAIR COLOR PRETREATMENT WITH SILICONE AND OILY OXIDANTS | HENKEL AG & CO. KGAA (DE) | 2014-06-19 | — | — | US | disclosed |
| US-20140166035-A1 | TWO PHASE DEVELOPER FOR MEDIUM OXIDATIVE COLOR CHANGE | HENKEL AG & CO. KGAA (DE) | 2014-06-19 | — | — | US | disclosed |
| US-8021438-B2 | Cationic acylpyridinium derivatives for use as bleach activators | HENKEL AG & CO. KGAA (DE) | 2011-09-20 | — | — | US | disclosed |
| US-20110146006-A1 | CATIONIC ACYLPYRIDINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20100146710-A1 | Reductive Decoloration of Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10143634-B2 | Thickening developer for oxidation dyes | CYBA, LPO, ACOX1 | KDM4E 2743/4885L3MBTL1 3490/4885TSHR 2121/4885 |
| US-20140165303-A1 | GENTLE HAIR COLOR PRETREATMENT WITH SILICONE AND OILY OXIDANTS | KRT18, DNMT1, PLOD1 | KDM4E 160/4885L3MBTL1 3434/4885TSHR 3166/4885 |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | KRT18, IK, SDHA | KDM4E 763/4885L3MBTL1 4521/4885TSHR 4746/4885 |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | KRT18, TK1, DPYD | KDM4E 1574/4885L3MBTL1 4543/4885TSHR 2998/4885 |
| US-20140165300-A1 | REDUCTION OF AMMONIA ODOR WHEN COLORING AND/OR LIGHTENING HAIR | OAT, KRT18, AKR7A2 | KDM4E 598/4885L3MBTL1 3482/4885TSHR 3497/4885 |
| US-20170252280-A1 | METHOD FOR SIMULTANEOUSLY AND PERMANENTLY RESHAPING AND COLORING KERATIN FIBERS | KRT18, CKMT1A; CKMT1B, DNMT1 | KDM4E 3053/4885L3MBTL1 2675/4885TSHR 3200/4885 |
| US-20140170223-A1 | POST OXIDATIVE HAIR TREATMENT AGENT WITH SILICONE | KRT18, MGMT, PLOD3 | KDM4E 240/4885L3MBTL1 3241/4885TSHR 4305/4885 |
| US-20110146006-A1 | CATIONIC ACYLPYRIDINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | KRT18, AADAC, KAT7 | KDM4E 1245/4885L3MBTL1 4425/4885TSHR 3523/4885 |
| US-20170273879-A1 | THICKENING DEVELOPER FOR OXIDATION DYES | CYBA, LPO, ACOX1 | KDM4E 2743/4885L3MBTL1 3490/4885TSHR 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.