Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | BCKDK | O14874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919840 | 0.81 | RAB9A (0.36) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL693361 | 0.79 | BCKDK (0.60) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL912683 | 0.78 | RAB9A (0.52) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL8920216 | 0.77 | DRD2 (0.34) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL912462 | 0.77 | RAB9A (0.49) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL2610281 | 0.76 | BCKDK (0.57) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL7018371 | 0.75 | BCKDK (0.49) | RAB9ABCKDKTP53KDM4ELMNA | |
| SCHEMBL4792978 | 0.73 | BCKDK (0.53) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL4769753 | 0.72 | HTR2A (0.45) | RAB9ABCKDKNPC1SMN1; SMN2TP53 | |
| SCHEMBL4767198 | 0.72 | CTSS (0.53) | RAB9ABCKDKTP53LMNACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |