Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | BCKDK | O14874 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919840 | 0.83 | RAB9A (0.36) | RAB9AACHEBCHEBCKDKTP53 | |
| SCHEMBL8917524 | 0.77 | RAB9A (0.44) | RAB9ABCKDKTP53NPC1SMN1; SMN2 | |
| SCHEMBL8917171 | 0.71 | DRD2 (0.39) | DRD2SLC6A4CCR3ACHEBCHE | |
| SCHEMBL8917725 | 0.68 | AVPR2 (0.39) | DRD2SLC6A4RAB9ATP53MAPT | |
| SCHEMBL8467925 | 0.68 | HTR1D (0.42) | DRD2SLC6A4RAB9AACHENPC1 | |
| SCHEMBL8919154 | 0.66 | MAOB (0.37) | DRD2SLC6A4ACHE | |
| SCHEMBL693361 | 0.64 | BCKDK (0.60) | RAB9ABCKDKTP53NPC1SMN1; SMN2 | |
| SCHEMBL912462 | 0.63 | RAB9A (0.49) | SLC6A4RAB9ABCKDKTP53NPC1 | |
| SCHEMBL912683 | 0.63 | RAB9A (0.52) | RAB9ABCKDKTP53NPC1SMN1; SMN2 | |
| SCHEMBL2610281 | 0.62 | BCKDK (0.57) | RAB9ABCKDKTP53NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |