Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BCKDK | O14874 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920216 | 0.83 | DRD2 (0.34) | RAB9ABCKDKSMN1; SMN2TP53NPC1 | |
| SCHEMBL8917524 | 0.81 | RAB9A (0.44) | RAB9AKDM4EBCKDKSMN1; SMN2TP53 | |
| SCHEMBL8919154 | 0.72 | MAOB (0.37) | MPOSCDMAOBACHE | |
| SCHEMBL8467925 | 0.72 | HTR1D (0.42) | RAB9ASMN1; SMN2NPC1SCDMAPT | |
| SCHEMBL8917725 | 0.72 | AVPR2 (0.39) | RAB9ATP53MAPTALDH1A1LMNA | |
| SCHEMBL16284423 | 0.71 | BCKDK (0.40) | RAB9AKDM4EBCKDKSMN1; SMN2TP53 | |
| SCHEMBL16078985 | 0.70 | BCKDK (0.42) | RAB9AKDM4EBCKDKSMN1; SMN2TP53 | |
| SCHEMBL5541613 | 0.69 | ESR1 (0.41) | MAOB | |
| SCHEMBL15186900 | 0.69 | CYP1A1 (0.34) | KDM4EBCKDKMAPTALDH1A1LMNA | |
| SCHEMBL693361 | 0.68 | BCKDK (0.60) | RAB9AKDM4EBCKDKSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |