Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873584 | 0.91 | LMNA (0.47) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8875248 | 0.91 | LMNA (0.41) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8916898 | 0.90 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL8874073 | 0.89 | LMNA (0.47) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8767453 | 0.88 | LMNA (0.42) | L3MBTL1LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL8917011 | 0.86 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8103313 | 0.84 | LMNA (0.45) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8915500 | 0.83 | LMNA (0.43) | L3MBTL1LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL8768228 | 0.83 | LMNA (0.45) | LMNAKMT2ASMN1; SMN2TSHRHTT | |
| SCHEMBL8917435 | 0.83 | LMNA (0.38) | L3MBTL1LMNASMN1; SMN2HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | claimed |