Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916898 | 0.89 | L3MBTL1 (0.52) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8873747 | 0.88 | LMNA (0.44) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8917593 | 0.86 | L3MBTL1 (0.43) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8870465 | 0.85 | LMNA (0.52) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8768360 | 0.79 | L3MBTL1 (0.50) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8874675 | 0.79 | L3MBTL1 (0.43) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8916345 | 0.79 | EGLN1 (0.51) | HTTSMN1; SMN2KMT2AEGLN1 | |
| SCHEMBL8097851 | 0.79 | LMNA (0.51) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8918674 | 0.79 | EGLN1 (0.46) | LMNAHTTSMN1; SMN2EGLN1 | |
| SCHEMBL8874939 | 0.77 | LMNA (0.44) | LMNATSHRHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |