Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875047 | 0.91 | SMN1; SMN2 (0.36) | LMNAHPGDHTTSMN1; SMN2CTDSP1 | |
| SCHEMBL8916746 | 0.90 | EGLN1 (0.42) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8767144 | 0.88 | LMNA (0.38) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8918674 | 0.85 | EGLN1 (0.46) | LMNAHPGDHTTSMN1; SMN2EGLN1 | |
| SCHEMBL8917593 | 0.83 | L3MBTL1 (0.43) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8917687 | 0.82 | MAPT (0.45) | LMNAHTTSMN1; SMN2PTGS2CA1 | |
| SCHEMBL8917617 | 0.82 | LIMK1 (0.42) | LIMK1LIMK2P4HTMPTGS2CA1 | |
| SCHEMBL8875237 | 0.82 | P4HTM (0.38) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8875475 | 0.80 | P4HTM (0.39) | LMNAHPGDHTTSMN1; SMN2P4HTM | |
| SCHEMBL8099449 | 0.79 | LMNA (0.37) | LMNAHPGDHTTSMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |