Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902021 | 0.87 | HTR1A (0.52) | METALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL14355885 | 0.80 | HTR1A (0.68) | ALDH1A1MAPK1MEN1KMT2AHTR1A | |
| SCHEMBL8912798 | 0.80 | DRD2 (0.51) | METALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8917051 | 0.78 | DRD2 (0.49) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15936238 | 0.76 | HTR1A (0.63) | METALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL30879319 | 0.76 | CYP19A1 (0.54) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL31219897 | 0.74 | NOX1 (0.50) | METALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL8900904 | 0.74 | DRD2 (0.56) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL29556577 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL17560070 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |