Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916565 | 0.94 | MAOA (0.41) | MAOAMAOBMCHR1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL8918152 | 0.80 | ACHE (0.39) | MCHR1MAPTTHRBACHEBRD3 | |
| Hydrochloric Acid SCHEMBL8917305 | 0.79 | ACHE (0.36) | MCHR1MAPTACHEHTR1ASLC6A4 | |
| SCHEMBL8917985 | 0.77 | CTSS (0.40) | MAOBMCHR1MAPTSLC6A4BAZ2B | |
| SCHEMBL8917035 | 0.75 | ACHE (0.46) | MCHR1MAPTACHETP53 | |
| SCHEMBL8916930 | 0.75 | SLC6A4 (0.52) | MCHR1MAPTHTR1ASLC6A4TP53 | |
| SCHEMBL8916713 | 0.73 | SLC6A4 (0.39) | MCHR1MAPTHTR1ASLC6A4BAZ2B | |
| SCHEMBL8917865 | 0.73 | MAPT (0.38) | MCHR1MAPTACHEBRD3TP53 | |
| SCHEMBL8916420 | 0.71 | CTSS (0.41) | MCHR1SLC6A4 | |
| SCHEMBL8916788 | 0.71 | CTSS (0.42) | MCHR1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |