Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117713 | 0.89 | CYP2C9 (0.34) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL16768860 | 0.88 | CYP2C9 (0.34) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL19274347 | 0.84 | KDM4E (0.31) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL18874580 | 0.83 | KDM4E (0.33) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL15031009 | 0.79 | TRPV1 (0.40) | CYP2C9KMT2AMAPTALDH1A1PKM | |
| SCHEMBL22193121 | 0.77 | HSD17B10 (0.47) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL13866571 | 0.77 | POLB (0.39) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL27517452 | 0.76 | POLB (0.45) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL12810686 | 0.75 | CYP2C9 (0.39) | CYP2C9MEN1KMT2ATDP1USP2 | |
| SCHEMBL23135781 | 0.75 | MYC (0.32) | MEN1KMT2ATDP1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170198333-A1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE FORMYL, SUCCINYL, METHYL SUCCINYL OR MYRISTOYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES | ENZO LIFE SCIENCES, INC. (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170198333-A1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE FORMYL, SUCCINYL, METHYL SUCCINYL OR MYRISTOYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES | ENZO LIFE SCIENCES, INC. (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170157272-A1 | FLUORESCENT PROBE FOR DETECTING DIPEPTIDYL PEPTIDASE IV | THE UNIVERSITY OF TOKYO (JP) | 2017-06-08 | — | — | US | disclosed |
| US-20170157272-A1 | FLUORESCENT PROBE FOR DETECTING DIPEPTIDYL PEPTIDASE IV | THE UNIVERSITY OF TOKYO (JP) | 2017-06-08 | — | — | US | disclosed |
| EP-2507252-B1 | HEAT-SENSITIVE SPIN-TRANSITION MATERIALS DOPED WITH ONE OR MORE FLUORESCENT AGENTS | CENTRE NAT RECH SCIENT (FR) | 2016-02-17 | — | — | EP | disclosed |
| US-9024022-B2 | Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof | CIS BIO INTERNATIONAL (FR) | 2015-05-05 | — | — | US | disclosed |
| US-9024022-B2 | Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof | CIS BIO INTERNATIONAL (FR) | 2015-05-05 | — | — | US | disclosed |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS BIO INTERNATIONAL (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS BIO INTERNATIONAL (FR) | 2011-09-29 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20110111446-A1 | THIOL DETECTION METHOD | RIKEN (JP) | 2011-05-12 | — | — | US | disclosed |
| US-20110111446-A1 | THIOL DETECTION METHOD | RIKEN (JP) | 2011-05-12 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | OGG1, UNG, MPG | CYP2C9 1499/4885MEN1 3062/4885KMT2A 707/4885 |
| US-20110111446-A1 | THIOL DETECTION METHOD | TST, GSTA1, TMT1A | CYP2C9 404/4885MEN1 4672/4885KMT2A 2586/4885 |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | CYP2C9 1673/4885MEN1 606/4885KMT2A 3286/4885 |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | GCKR, SYMPK, SUCNR1 | CYP2C9 1673/4885MEN1 606/4885KMT2A 3286/4885 |
| US-20170198333-A1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE FORMYL, SUCCINYL, METHYL SUCCINYL OR MYRISTOYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES | EMG1, SPR, SHMT1 | CYP2C9 3081/4885MEN1 2189/4885KMT2A 574/4885 |
| US-20170157272-A1 | FLUORESCENT PROBE FOR DETECTING DIPEPTIDYL PEPTIDASE IV | DPP4, DPP7, DPP3 | CYP2C9 3084/4885MEN1 3096/4885KMT2A 2722/4885 |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | GCKR, SYMPK, SUCNR1 | CYP2C9 1673/4885MEN1 606/4885KMT2A 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.