Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692150 | 0.82 | APP (0.33) | CA2 | |
| SCHEMBL3450884 | 0.78 | HTR2A (0.30) | — | |
| SCHEMBL2528409 | 0.78 | MAOA (0.31) | — | |
| SCHEMBL8954134 | 0.77 | MGLL (0.35) | — | |
| SCHEMBL239869 | 0.77 | LMNA (0.33) | POLBCA2 | |
| SCHEMBL11863151 | 0.76 | SIGMAR1 (0.32) | — | |
| SCHEMBL17929 | 0.75 | LTA4H (0.35) | POLB | |
| SCHEMBL9473446 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL216358 | 0.73 | — | — | |
| SCHEMBL28252911 | 0.73 | LTA4H (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614562-A | Method of treating drug resistant tumor cells using organoselenones | THE UNIVERSITY OF SOURTHERN CALIFORNIA (US) | 1997-03-25 | — | — | US | disclosed |