Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451179 | 0.82 | METAP2 (0.47) | POLBMAPTSMN1; SMN2METAP2CNR2 | |
| SCHEMBL8920514 | 0.76 | CTSL (0.53) | MAPTMETAP2MMP1MMP9MMP13 | |
| SCHEMBL8920506 | 0.76 | CTSL (0.53) | MAPTMETAP2MMP1MMP9MMP13 | |
| SCHEMBL5041804 | 0.76 | ADAMTS5 (0.55) | POLBTP53ADAMTS5ACHEALDH1A1 | |
| SCHEMBL28644268 | 0.75 | ADAMTS5 (0.57) | POLBMAPTSMN1; SMN2TP53ADAMTS5 | |
| SCHEMBL5573297 | 0.74 | ADAMTS5 (0.73) | POLBMAPTADAMTS5CNR2KMT2A | |
| SCHEMBL5573300 | 0.74 | ADAMTS5 (0.73) | POLBMAPTADAMTS5CNR2KMT2A | |
| SCHEMBL8451184 | 0.74 | METAP2 (0.47) | POLBMAPTSMN1; SMN2METAP2ALDH1A1 | |
| SCHEMBL8920959 | 0.74 | METAP2 (0.52) | POLBMAPTSMN1; SMN2METAP2BCHE | |
| SCHEMBL5574109 | 0.74 | ALDH1A1 (0.47) | POLBTP53ADAMTS5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5252721-A | S3 N chelating compounds | NEORX CORPORATION (US) | 1993-10-12 | — | — | US | disclosed |