SCHEMBL892045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL441786	0.82	ALDH1A1 (0.37)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL892409	0.81	CTRB1 (0.36)	MMP8ALDH1A1
	SCHEMBL891916	0.81	TSHR (0.32)	—
	SCHEMBL9286681	0.80	MMP8 (0.37)	MMP8PKMKMT2AKDM4EMEN1
	SCHEMBL12482713	0.79	MMP8 (0.35)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL954289	0.78	MMP8 (0.43)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL14504422	0.78	MMP8 (0.43)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL17898134	0.77	MMP8 (0.40)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL20725836	0.76	MMP8 (0.37)	MMP8ALDH1A1PKMKMT2AKDM4E
	SCHEMBL891445	0.75	TSHR (0.33)	KDM4ENPSR1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.