Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920356 | 0.84 | AKR1C3 (0.40) | ALDH1A1HSD17B10HPGDALOX15AKR1C3 | |
| SCHEMBL9858027 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10HPGDALOX15AKR1C3 | |
| SCHEMBL8922784 | 0.76 | HSD17B10 (0.45) | ALDH1A1HSD17B10HPGDALOX15SMN1; SMN2 | |
| SCHEMBL8925211 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDALOX15SMN1; SMN2 | |
| SCHEMBL8922826 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDALOX15AKR1C3 | |
| SCHEMBL8922352 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDALOX15AKR1C3 | |
| SCHEMBL8922256 | 0.73 | HSD17B10 (0.49) | ALDH1A1HSD17B10HPGDALOX15SMN1; SMN2 | |
| SCHEMBL8923602 | 0.72 | PIK3CA (0.42) | ALDH1A1AKR1C3SMN1; SMN2PRKDCKMT2A | |
| SCHEMBL8922167 | 0.71 | HSD17B10 (0.57) | ALDH1A1HSD17B10HPGDALOX15AKR1C3 | |
| SCHEMBL9133599 | 0.68 | ALDH1A1 (0.80) | ALDH1A1HSD17B10HPGDALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |