Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922784 | 0.80 | HSD17B10 (0.45) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8922256 | 0.77 | HSD17B10 (0.49) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8923374 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8922826 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8966838 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8922352 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL9857292 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL2049182 | 0.68 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9857777 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8923602 | 0.67 | PIK3CA (0.42) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | claimed |
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |