Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767793 | 0.87 | POLB (0.53) | POLBMAPTHTTPKMPPARA | |
| SCHEMBL8924220 | 0.83 | TAS1R3 (0.54) | POLBMAPTHTTPPARAABCB11 | |
| SCHEMBL8926594 | 0.75 | PPARA (0.52) | POLBMAPTHTTPKMPPARA | |
| SCHEMBL1417870 | 0.73 | PPARA (0.71) | MAPTHTTPPARAABCB11CYP1A2 | |
| SCHEMBL9107793 | 0.71 | TAS1R3 (0.47) | POLBMAPTHTTPPARAABCB11 | |
| SCHEMBL8768601 | 0.71 | PPARG (0.70) | MAPTHTTPPARAPPARGPPARD | |
| SCHEMBL8768837 | 0.70 | PPARG (0.82) | PPARAPPARGPPARD | |
| SCHEMBL1417534 | 0.69 | FBP1 (0.62) | POLBMAPTHTTPPARAABCB11 | |
| SCHEMBL8768942 | 0.69 | KMT2A (0.57) | POLBMAPTHTTTSHRKMT2A | |
| SCHEMBL8540230 | 0.68 | PKM (0.56) | POLBMAPTHTTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |