Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725974 | 0.75 | PTGS2 (0.42) | PTGS2PTGS1ENPP2 | |
| SCHEMBL7495875 | 0.68 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL7495881 | 0.68 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL8925412 | 0.68 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL7495878 | 0.68 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL2376239 | 0.59 | ENPP2 (0.72) | PTGS2ENPP2 | |
| SCHEMBL482627 | 0.59 | PKM (0.47) | — | |
| SCHEMBL992171 | 0.59 | LMNA (0.52) | — | |
| SCHEMBL6746191 | 0.58 | CA12 (0.68) | PTGS2 | |
| SCHEMBL28996978 | 0.58 | ENPP2 (0.46) | PTGS2PTGS1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698584-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1997-12-16 | — | — | US | disclosed |