Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725655 | 0.78 | PTGS2 (0.37) | PTGS2ENPP2PTGS1 | |
| SCHEMBL8925415 | 0.75 | PTGS2 (0.38) | PTGS2ENPP2PTGS1 | |
| SCHEMBL726270 | 0.73 | TAAR1 (0.36) | — | |
| SCHEMBL19315862 | 0.73 | — | — | |
| SCHEMBL4429077 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL3672322 | 0.69 | LMNA (0.31) | PTGS2 | |
| SCHEMBL12535871 | 0.69 | IDO1 (0.44) | — | |
| SCHEMBL2376239 | 0.68 | ENPP2 (0.72) | PTGS2ENPP2 | |
| SCHEMBL5140237 | 0.67 | ALDH1A1 (0.43) | PTGS2ENPP2PTGS1 | |
| SCHEMBL29429160 | 0.67 | ENPP2 (0.38) | PTGS2ENPP2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018109781-A1 | A PROCESS FOR THE PREPARATION OF FIROCOXIB | SEQUENT SCIENTIFIC LIMITED (IN) | 2018-06-21 | — | — | WO | disclosed |
| EP-2585431-B1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2017-09-06 | — | — | EP | disclosed |
| EP-2585431-B1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-9657435-B2 | Metal free bleaching composition | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-9657435-B2 | Metal free bleaching composition | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-9657435-B2 | Metal free bleaching composition | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20130117941-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130117941-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130117941-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| EP-2585431-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012000846-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012000846-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2012-01-05 | — | — | WO | disclosed |
| EP-1218366-B8 | METHOD FOR PRODUCING COX-2 INHIBITORS | MERIAL SAS (FR) | 2005-11-09 | — | — | EP | disclosed |
| EP-1218366-B1 | METHOD FOR PRODUCING COX-2 INHIBITORS | MERIAL SAS (FR) | 2005-09-14 | — | — | EP | disclosed |
| US-6541646-B2 | Reacting an oxirane compound containing phenylsulfonyl group with an acid in an anhydrous medium to form an intermediate, reacting the intermediate with a storng base in an aprotic solvent to form an ester compound,dehydrating the ester comp. | MERIAL (FR) | 2003-04-01 | — | — | US | disclosed |
| US-20030028036-A1 | Method of preparing COX-2 inhibitors | MERIAL (FR) | 2003-02-06 | — | — | US | disclosed |
| EP-1218366-A2 | METHOD FOR PRODUCING COX-2 INHIBITORS | MERIAL (FR) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001027098-A2 | METHOD FOR PRODUCING COX-2 INHIBITORS | MERIAL (FR) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028036-A1 | Method of preparing COX-2 inhibitors | PTGS2, PTGS1, PTGES2 | PTGS2 1/4885ENPP2 1483/4885PTGS1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.