Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925017 | 0.88 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8925113 | 0.88 | CA12 (0.45) | ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8926916 | 0.87 | PDE7A (0.41) | LMNA | |
| SCHEMBL8925087 | 0.86 | PDE4B (0.41) | MAPTHPGD | |
| SCHEMBL8926706 | 0.85 | FLT1 (0.39) | PTGDR2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6937449 | 0.83 | SLC9A1 (0.61) | — | |
| SCHEMBL1431054 | 0.81 | RHEB (0.39) | RHEBPTGDR2ALDH1A1LMNAHPGD | |
| SCHEMBL8925101 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGD | |
| SCHEMBL8926370 | 0.80 | SLC6A9 (0.36) | — | |
| SCHEMBL8926776 | 0.79 | PTGS1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058001-C | 4-Mercaptobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5696167-A | 4-mercaptobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-09 | — | — | US | disclosed |
| CN-1134413-A | 4-Mercaptobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-10-30 | — | — | CN | disclosed |