Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514264 | 0.83 | SYK (0.50) | RAB9ASMN1; SMN2TP53ALDH1A1KMO | |
| SCHEMBL9836317 | 0.79 | PPOX (0.40) | RAB9ASMN1; SMN2L3MBTL1HPGDKDM4E | |
| SCHEMBL8555879 | 0.78 | L3MBTL1 (0.46) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7081041 | 0.77 | LMNA (0.41) | HPGD | |
| SCHEMBL9620179 | 0.77 | PPOX (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL4600261 | 0.77 | NPC1 (0.52) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL17010215 | 0.77 | ALOX5 (0.47) | MRGPRX4L3MBTL1CYP1A2CYP2C19PPARG | |
| SCHEMBL8887423 | 0.76 | NR1I2 (0.39) | HPGDALDH1A1 | |
| SCHEMBL9533072 | 0.76 | PPOX (0.43) | NPC1RAB9APPOX | |
| SCHEMBL10574907 | 0.76 | GLA (0.41) | SMN1; SMN2L3MBTL1ALDH1A1PPOXPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602077-A | CONTROLLING GROWTH OF UNDESIRED VEGETATION IN PLANTATION CROPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| US-5567670-A | TETRAHYDROTRIAZINE-DIONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0623117-A1 | PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014073-A1 | PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |