Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | PTAFR | P25105 | 18/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etizolam SCHEMBL42920 | 0.88 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL30665015 | 0.88 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928436 | 0.86 | OPRK1 (0.77) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL11508119 | 0.85 | PTAFR (0.65) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| Etizolam SCHEMBL28142121 | 0.84 | OPRK1 (0.69) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| Etizolam SCHEMBL10869413 | 0.84 | OPRK1 (0.90) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL28086661 | 0.81 | OPRK1 (0.85) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928483 | 0.80 | OPRK1 (0.84) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8878960 | 0.80 | OPRK1 (0.74) | OPRK1PDE4DPTAFRGABRA1GABRA5 | |
| SCHEMBL8928481 | 0.79 | OPRK1 (0.84) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |