Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295364 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL3298464 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL22440483 | 0.73 | LTA4H (0.32) | ALDH1A1TSHR | |
| SCHEMBL30434458 | 0.72 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHRATMKDM4E | |
| SCHEMBL10755521 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL704146 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL2163736 | 0.70 | RBP4 (0.39) | ALDH1A1KDM4EGAARXRARXRB | |
| SCHEMBL988385 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL5000032 | 0.67 | TDP1 (0.41) | ALDH1A1TDP1TSHRATMCA2 | |
| SCHEMBL272815 | 0.66 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRATMCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756595-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC (CA) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995029176-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1995-11-02 | — | — | WO | disclosed |