SCHEMBL8932250

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21541330	1.00	ALDH1A1 (0.53)	ALDH1A1GABRPGABRDGABRA1GABRB1
	SCHEMBL12557459	0.85	CASP2 (0.65)	CASP2NAAAFAAHNOD1TP53
	SCHEMBL22516427	0.84	ALDH1A1 (0.53)	ALDH1A1GABRPGABRDGABRA1GABRB1
	SCHEMBL21935015	0.83	GABRP (0.52)	ALDH1A1GABRPGABRDGABRA1GABRB1
	SCHEMBL1518045	0.83	ALDH1A1 (0.57)	ALDH1A1CASP2MCL1CNR1NAAA
	SCHEMBL16181357	0.82	ALDH1A1 (0.80)	ALDH1A1CASP2MCL1CNR1NAAA
	SCHEMBL13785511	0.81	NOD1 (0.52)	ALDH1A1MMP2MMP9MMP8MMP12
	SCHEMBL14519216	0.81	NOD1 (0.52)	ALDH1A1MMP2MMP9MMP8MMP12
	SCHEMBL23429685	0.80	ALDH1A1 (0.53)	ALDH1A1CASP2MCL1CNR1CTSD
	SCHEMBL12059217	0.80	ALDH1A1 (0.53)	ALDH1A1CASP2MCL1CNR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.