SCHEMBL8932415

SCHEMBL8932415

COc1ccc(CSC2CN(C)C(=NC(C)=O)N(C)C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 3/20 0.37
KDM4E B2RXH2 2/20 0.37
KMT2A Q03164 2/20 0.37
PKM P14618 1/20 0.37
IDO1 P14902 2/20 0.37
TP53 P04637 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932422 0.80 CMA1 (0.45) ALDH1A1HPGDMAPTKMT2AIDO1
SCHEMBL8932639 0.79 NAAA (0.41) ALDH1A1IDO1
SCHEMBL8932463 0.77 NAAA (0.40) ALDH1A1SMN1; SMN2KMT2APKMIDO1
SCHEMBL8932507 0.74 ALDH1A1 (0.39) ALDH1A1HPGDSMN1; SMN2MAPTTP53
SCHEMBL8932387 0.73 POLB (0.40) ALDH1A1MAPTGAATP53
Hydrochloric Acid SCHEMBL10506096 0.72 IDO1 (0.40) HPGDKMT2AIDO1
SCHEMBL8440250 0.72 ALDH1A1 (0.42) ALDH1A1HPGDSMN1; SMN2MAPTGAA
SCHEMBL7454797 0.72 ALDH1A1 (0.42) ALDH1A1HPGDSMN1; SMN2MAPTGAA
SCHEMBL8604028 0.71 IDO1 (0.43) ALDH1A1HPGDSMN1; SMN2MAPTGAA
SCHEMBL8439880 0.71 IDO1 (0.43) ALDH1A1HPGDSMN1; SMN2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996026939-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-06 WO disclosed