Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911940 | 0.83 | CYP2C9 (0.36) | HTTL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29285349 | 0.78 | LTA4H (0.53) | LTA4HHTTTDP1L3MBTL1IDO1 | |
| SCHEMBL8933405 | 0.75 | KEAP1 (0.41) | LTA4HTDP1L3MBTL1ATMALDH1A1 | |
| SCHEMBL19309384 | 0.73 | HTR1A (0.40) | LTA4HL3MBTL1IDO1ALDH1A1ALOX12 | |
| SCHEMBL19308138 | 0.73 | ACHE (0.39) | L3MBTL1IDO1ALDH1A1ALOX12LMNA | |
| SCHEMBL3387953 | 0.73 | IDO1 (0.52) | LTA4HIDO1ALDH1A1ALOX12SMN1; SMN2 | |
| SCHEMBL11655848 | 0.72 | RAB9A (0.43) | LTA4HHTTTDP1L3MBTL1IDO1 | |
| SCHEMBL29285346 | 0.71 | CA12 (0.41) | LTA4HL3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL5519899 | 0.71 | IDO1 (0.50) | LTA4HIDO1ALDH1A1ALOX12SMN1; SMN2 | |
| SCHEMBL12934387 | 0.70 | LTA4H (0.67) | LTA4HHTTTDP1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |