Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470303 | 0.82 | GABRA1 (0.41) | CCNE2CCNE1CDK2GABRA1GABRA5 | |
| SCHEMBL30320290 | 0.80 | LMNA (0.57) | CCNE2CCNE1CDK2LMNAAURKA | |
| SCHEMBL10471802 | 0.80 | GABRA1 (0.57) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7380121 | 0.80 | LMNA (0.57) | CCNE2CCNE1CDK2LMNAAURKA | |
| SCHEMBL7955851 | 0.80 | CHRM1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8933416 | 0.78 | GABRA3 (0.35) | S100A4GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL10469940 | 0.78 | GABRA1 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8933547 | 0.76 | CCNE2 (0.34) | CCNE2CCNE1CDK2GABRA1GABRA5 | |
| SCHEMBL7376595 | 0.76 | GABRA1 (0.58) | S100A4GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL8933492 | 0.75 | GABRA1 (0.67) | CCNE2CCNE1CDK2GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |