SCHEMBL8934248

SCHEMBL8934248

CSc1c(C)cc(N)c(N)c1SC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TSHR P16473 3/20 0.40
MAPK1 P28482 1/20 0.40
CD44 P16070 2/20 0.36
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 4/20 0.35
TP53 P04637 1/20 0.35
CASP1 P29466 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16781734 0.83
SCHEMBL7190301 0.74 NPC1 (0.31)
SCHEMBL8934247 0.74 NPC1 (0.31)
SCHEMBL9180441 0.72 ALDH1A1 (0.46) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL9578911 0.71 CD44 (0.41) CYP3A4TSHRCD44ALDH1A1TDP1
SCHEMBL21450712 0.71 CYP3A4 (0.40) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL19029861 0.71 CASP1 (0.41) CYP3A4TSHRMAPK1CD44ALDH1A1
SCHEMBL175685 0.70 NPC1 (0.35) CYP3A4TSHRALDH1A1TDP1TP53
SCHEMBL175015 0.70 ALDH1A1 (0.39) CYP3A4TSHRALDH1A1TDP1TP53
SCHEMBL9131451 0.69 PTPN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8041156-A None JP disclosed
US-12637538-B2 Coating compositions PPG INDUSTRIES OHIO, INC. (US) 2026-05-26 US disclosed
EP-4017898-B1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG IND OHIO INC (US) 2026-04-29 EP disclosed
US-20240368437-A1 ADHESIVE COMPOSITION WITH LIGHTWEIGHT FILLER PPG INDUSTRIES OHIO, INC. (US) 2024-11-07 US disclosed
EP-4399253-A1 ADHESIVE COMPOSITION WITH LIGHTWEIGHT FILLER PPG Industries Ohio, Inc. (US) 2024-07-17 EP disclosed
EP-4017896-B1 COATING COMPOSITIONS PPG IND OHIO INC (US) 2024-06-12 EP disclosed
WO-2023039504-A1 ADHESIVE COMPOSITION WITH LIGHTWEIGHT FILLER PPG INDUSTRIES OHIO, INC. (US) 2023-03-16 WO disclosed
US-20220325129-A1 COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-10-13 US disclosed
US-20220282115-A1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG INDUSTRIES OHIO, INC. (US) 2022-09-08 US disclosed
US-20220275240-A1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG INDUSTRIES OHIO, INC. (US) 2022-09-01 US disclosed
EP-4017896-A1 COATING COMPOSITIONS PPG Industries Ohio Inc. (US) 2022-06-29 EP disclosed
EP-4018016-A1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG Industries Ohio Inc. (US) 2022-06-29 EP disclosed
WO-2021040867-A1 COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2021-03-04 WO disclosed
WO-2021040864-A1 COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2021-03-04 WO disclosed
WO-2021040868-A1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG INDUSTRIES OHIO, INC. (US) 2021-03-04 WO disclosed
WO-2021040865-A1 SYSTEMS AND METHODS FOR IMPROVED LAP SHEAR STRENGTH AND DISPLACEMENT OF TWO-COMPONENT STRUCTURAL ADHESIVES PPG INDUSTRIES OHIO, INC. (US) 2021-03-04 WO disclosed
JP-H0841156-A PRODUCTION OF COLD-CURING WATERPROOFING COATING FILM MATERIAL HODOGAYA CHEM CO LTD 1996-02-13 JP disclosed
US-5166299-A Polyureas; flexbility, resilience; rolls ETHYL CORPORATION (US) 1992-11-24 US disclosed
US-5166299-A Polyureas; flexbility, resilience; rolls ETHYL CORPORATION (US) 1992-11-24 US disclosed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637538-B2 Coating compositions AOC1, AOC2, H1-2 CYP3A4 2047/4885TSHR 2968/4885MAPK1 3510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.