Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 11/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CREB1 | P16220 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934583 | 0.87 | ACHE (0.54) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL9139841 | 0.81 | HPGD (0.80) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL4053857 | 0.80 | KDM4E (0.80) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL30738943 | 0.79 | ACHE (0.73) | KDM4ECYP2C9HPGDCYP2C19CYP1A2 | |
| SCHEMBL8934497 | 0.79 | CYP2D6 (0.52) | CYP1A2ALDH1A1CYP3A4EGFRACHE | |
| SCHEMBL28848654 | 0.76 | KDM5A (0.52) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL4783697 | 0.75 | ALDH1A1 (0.67) | KDM4ECYP2C9HPGDCYP2C19CYP1A2 | |
| SCHEMBL8429610 | 0.74 | DYRK1A (0.48) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| Efloxate SCHEMBL309159 | 0.73 | KDM4E (1.00) | KDM4EPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL8427304 | 0.72 | DYRK1A (0.52) | KDM4EPOLBCYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |