Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.53 |
| ▸ | GABRD | O14764 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.53 |
| ▸ | GABRE | P78334 | 2/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934550 | 0.87 | KDM4E (0.66) | ACHEPLK1BACE1PKMGABRP | |
| SCHEMBL30738943 | 0.82 | ACHE (0.73) | ACHEPLK1BACE1PKMGABRP | |
| SCHEMBL4783697 | 0.80 | ALDH1A1 (0.67) | ACHEPLK1BACE1PKMGABRP | |
| SCHEMBL8934497 | 0.80 | CYP2D6 (0.52) | ACHEPLK1BACE1PKMGABRP | |
| SCHEMBL9141348 | 0.79 | ALDH1A1 (0.65) | ACHEPKMABCB1MAPTALDH1A1 | |
| SCHEMBL12835534 | 0.79 | ABCB1 (0.55) | ACHEPLK1BACE1PKMGABRP | |
| Flavodic Acid SCHEMBL867342 | 0.77 | KDM4E (0.76) | ABCB1MAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8934562 | 0.75 | MEN1 (0.67) | ACHEPLK1BACE1PKMGABRP | |
| SCHEMBL7608398 | 0.74 | CREB1 (0.68) | ABCB1MAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL25301059 | 0.72 | ABCB1 (0.65) | ACHEPLK1BACE1PKMGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |