Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 13/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934556 | 0.80 | ADRA2A (0.48) | — | |
| SCHEMBL8934533 | 0.80 | NPY1R (0.50) | SMN1; SMN2GAAPOLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8934527 | 0.79 | CRHBP (0.40) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL8934612 | 0.74 | TP53 (0.36) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL8934581 | 0.74 | TP53 (0.36) | MAPTSMN1; SMN2GAATP53L3MBTL1 | |
| SCHEMBL8934510 | 0.74 | NPC1 (0.41) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL8934521 | 0.73 | THRB (0.39) | MAPTGAATP53POLBKDM4E | |
| SCHEMBL9380526 | 0.71 | ALDH1A1 (0.44) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL8934504 | 0.70 | NPY1R (0.48) | SMN1; SMN2GAAPOLBALDH1A1HPGD | |
| SCHEMBL9376799 | 0.68 | DNMT1 (0.35) | MAPTSMN1; SMN2GAATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |