Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | GAA | P10253 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934556 | 0.82 | ADRA2A (0.48) | AOC3 | |
| SCHEMBL8934581 | 0.80 | TP53 (0.36) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL8934592 | 0.74 | MAPT (0.37) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL8934533 | 0.74 | NPY1R (0.50) | POLBGAASMN1; SMN2ALDH1A1AOC3 | |
| Hydrochloric Acid SCHEMBL8934527 | 0.73 | CRHBP (0.40) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL8934510 | 0.72 | NPC1 (0.41) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL8934521 | 0.72 | THRB (0.39) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL9380526 | 0.69 | ALDH1A1 (0.44) | TP53POLBRXFP1THRBMAPT | |
| SCHEMBL8934538 | 0.67 | ALDH1A1 (0.48) | TP53POLBRXFP1MAPTGAA | |
| SCHEMBL9375701 | 0.66 | DNMT1 (0.35) | TP53POLBRXFP1THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |