Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397015 | 0.81 | SCN9A (0.61) | RAB9APOLBNPC1 | |
| SCHEMBL4816702 | 0.81 | SCN9A (0.61) | RAB9APOLBNPC1 | |
| SCHEMBL8935256 | 0.81 | POLB (0.59) | RAB9APOLBNPC1HPGDSMN1; SMN2 | |
| SCHEMBL8935386 | 0.80 | CARM1 (0.51) | CARM1PRMT6LTA4H | |
| SCHEMBL8935341 | 0.79 | LTA4H (0.53) | RAB9APOLBNPC1CARM1PRMT6 | |
| SCHEMBL8935415 | 0.76 | CARM1 (0.58) | RAB9ANPC1CARM1PRMT6LTA4H | |
| SCHEMBL8935290 | 0.76 | CARM1 (0.60) | CARM1PRMT6LTA4HSMN1; SMN2GAA | |
| SCHEMBL8935452 | 0.76 | SCN9A (0.68) | CARM1PRMT6LTA4H | |
| SCHEMBL8935244 | 0.75 | MAOB (0.69) | — | |
| SCHEMBL14323980 | 0.75 | MAOB (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |