Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935310 | 0.86 | MAOB (0.55) | MAOB | |
| SCHEMBL8935286 | 0.84 | MAOB (0.54) | MAOBMAOAMDM4MDM2MEN1 | |
| SCHEMBL8935376 | 0.80 | MAOB (0.60) | MAOBADAMTS4MMP13FFAR1FFAR4 | |
| SCHEMBL8935232 | 0.77 | FFAR1 (0.51) | MEN1KMT2AFFAR1 | |
| SCHEMBL8935251 | 0.76 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL8935296 | 0.74 | ALOX5 (0.60) | MAOBMAOAFFAR1ALOX5 | |
| Hydrochloric Acid SCHEMBL30002091 | 0.74 | MAOB (0.56) | MAOBMAOAADAMTS4MMP13KMT2A | |
| SCHEMBL4759812 | 0.73 | MAOB (0.65) | MAOBMAOAADAMTS4MMP13FFAR1 | |
| SCHEMBL13462731 | 0.72 | MAOB (0.71) | MAOBMAOAADAMTS4MMP13KMT2A | |
| SCHEMBL8935297 | 0.72 | MAOB (0.59) | MAOBMAOAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |