Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP5 | P24593 | 3/20 | 0.43 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9602865 | 0.81 | ALOX15 (0.50) | IGFBP5IGFBP3 | |
| SCHEMBL8936126 | 0.80 | IGFBP5 (0.44) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| 7-Chlorokynurenic Acid SCHEMBL29386783 | 0.76 | IGFBP3 (0.47) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| 7-Chlorokynurenic Acid SCHEMBL31238955 | 0.76 | IGFBP3 (0.47) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| SCHEMBL15129999 | 0.76 | ALDH1A1 (0.51) | IGFBP3POLBKMT2ADHODHKMO | |
| 7-Chlorokynurenic Acid SCHEMBL157187 | 0.76 | IGFBP3 (0.47) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| SCHEMBL8337206 | 0.75 | DHODH (0.43) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| 7-Chlorokynurenic Acid SCHEMBL20770380 | 0.75 | IGFBP3 (0.46) | IGFBP5IGFBP3POLBKMT2ADHODH | |
| Hydrochloric Acid SCHEMBL5410407 | 0.74 | DHODH (0.42) | IGFBP3POLBKMT2ADHODHKMO | |
| SCHEMBL5397913 | 0.71 | KMO (0.46) | IGFBP5POLBKMT2ADHODHKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510338-A | ADMINISTERING TO A MAMMAL TO RELIEVE PAIN AND TO TREAT CONVULSIONS, CEREBRAL ISCHEMIC DAMAGE, AND EMESIS | GUILFORD PHARMACEUTICALS INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5342946-A | Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA ionotropic excitatory amino acid receptors | GUILFORD PHARMACEUTICALS INC. (US) | 1994-08-30 | — | — | US | disclosed |