SCHEMBL8936382

SCHEMBL8936382

C=CCN(C)S(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
GSTO1 P78417 3/20 0.32
MAPT P10636 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936368 0.86 ALDH1A1 (0.34) ALDH1A1L3MBTL1GSTO1
SCHEMBL8936415 0.86 GSTO1 (0.41) ALDH1A1L3MBTL1GSTO1MAPT
SCHEMBL8936419 0.84 GSTO1 (0.45) ALDH1A1L3MBTL1GSTO1
SCHEMBL8936351 0.81 ALDH1A1 (0.32) ALDH1A1L3MBTL1GSTO1MAPT
SCHEMBL3555928 0.80 TSHR (0.34) ALDH1A1L3MBTL1NPSR1MAPT
SCHEMBL3545755 0.79 MMP2 (0.36) ALDH1A1L3MBTL1MAPT
SCHEMBL2964335 0.79
SCHEMBL2964332 0.78 PPARD (0.32)
SCHEMBL8936370 0.77 MEN1 (0.39) ALDH1A1L3MBTL1GSTO1MAPT
SCHEMBL2963126 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486610-A HERBICIDE INTERMEDIATES UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-01-23 US disclosed
US-5324854-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-06-28 US disclosed
EP-0598774-A1 BENZENESULFONAMIDE DERIVATIVES AS HERBICIDES UNIROYAL CHEMICAL COMPANY, Inc. (US) 1994-06-01 EP disclosed
WO-1993003019-A1 BENZENESULFONAMIDE DERIVATIVES AS HERBICIDES UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-02-18 WO disclosed
US-5169430-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-12-08 US disclosed