SCHEMBL8936368

SCHEMBL8936368

CCCN(C)S(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GSTO1 P78417 5/20 0.34
HSP90AA1 P07900 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KMT2A Q03164 1/20 0.32
RXFP1 Q9HBX9 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
BRD9 Q9H8M2 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936419 0.89 GSTO1 (0.45) ALDH1A1L3MBTL1GSTO1SMN1; SMN2RXFP1
SCHEMBL8936415 0.87 GSTO1 (0.41) ALDH1A1L3MBTL1GSTO1SMN1; SMN2KMT2A
SCHEMBL8936382 0.86 ALDH1A1 (0.33) ALDH1A1L3MBTL1GSTO1
SCHEMBL8936351 0.83 ALDH1A1 (0.32) ALDH1A1L3MBTL1GSTO1SMN1; SMN2KMT2A
SCHEMBL3555928 0.82 TSHR (0.34) ALDH1A1L3MBTL1KMT2ATSHRBRD9
SCHEMBL3545755 0.81 MMP2 (0.36) ALDH1A1L3MBTL1KMT2ATSHRHTT
SCHEMBL6049391 0.81 SCN9A (0.34) ALDH1A1SMN1; SMN2
SCHEMBL8936370 0.79 MEN1 (0.39) ALDH1A1L3MBTL1GSTO1SMN1; SMN2KMT2A
SCHEMBL3546133 0.76 MEN1 (0.31) ALDH1A1L3MBTL1KMT2ATSHR
SCHEMBL6049451 0.76 P2RX7 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486610-A HERBICIDE INTERMEDIATES UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-01-23 US disclosed
US-5324854-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-06-28 US disclosed
US-5169430-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-12-08 US disclosed