Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938187 | 0.90 | CCR5 (0.47) | BCHE | |
| SCHEMBL8938362 | 0.89 | HTR1A (0.44) | OPRM1SLC7A5 | |
| SCHEMBL8938340 | 0.88 | SLC6A4 (0.44) | OPRM1 | |
| SCHEMBL8938423 | 0.85 | OPRM1 (0.42) | OPRM1 | |
| SCHEMBL8938428 | 0.84 | HRH3 (0.58) | — | |
| SCHEMBL8938354 | 0.83 | OPRM1 (0.43) | OPRM1 | |
| SCHEMBL8938400 | 0.82 | HRH3 (0.44) | BCHE | |
| SCHEMBL8938348 | 0.81 | HTR2A (0.41) | — | |
| SCHEMBL8938195 | 0.81 | SIGMAR1 (0.44) | — | |
| SCHEMBL8938244 | 0.81 | OPRD1 (0.47) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5410046-A | Selective muscarinic receptor antagonists | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0350309-B1 | PIPERIDINE DERIVATIVES | Pfizer Limited (GB) | 1992-11-11 | — | — | EP | disclosed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0350309-A1 | Piperidine derivatives | Pfizer Limited (GB) | 1990-01-10 | — | — | EP | disclosed |