Diphenylmethane

Diphenylmethane

SCHEMBL8938749

O=C=NCN=C=O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.55
CYP3A4 P08684 2/20 0.45
TSHR P16473 1/20 0.45
PLA2G10 O15496 1/20 0.41
PLA2G2A P14555 1/20 0.41
LMNA P02545 1/20 0.41
MIF P14174 3/20 0.40
TRPA1 O75762 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
SLC22A2 O15244 1/20 0.39
LTA4H P09960 1/20 0.39
IDH1 O75874 1/20 0.38
CYP2E1 P05181 1/20 0.38
CYP2A6 P11509 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP2A13 Q16696 1/20 0.38
EPAS1 Q99814 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL10971266 0.86 CALM1 (0.55) CALM1CYP3A4TSHRPLA2G10PLA2G2A
Biphenyl SCHEMBL15542 0.81 ALDH1A1 (0.45) CYP3A4TSHRLMNAALDH1A1CA12
Diphenylmethane SCHEMBL28176599 0.81 MIF (0.50) CALM1CYP3A4TSHRPLA2G10PLA2G2A
Benzene SCHEMBL21082728 0.80
Benzene SCHEMBL19066305 0.80
Benzene SCHEMBL740866 0.80
Diphenylmethane SCHEMBL3468615 0.79 CALM1 (0.46) CALM1CYP3A4TSHRPLA2G10PLA2G2A
SCHEMBL454426 0.78 MEN1 (0.39) CYP3A4TSHRLMNAMIFTRPA1
Phenol SCHEMBL7102161 0.77 TDP1 (0.50) LMNATRPA1LTA4HHIF1ACA12
Toluene SCHEMBL11027465 0.77 LMNA (0.50) CYP3A4TSHRLMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148750-A1 THERMO-MECHANICAL-OPTICAL BONDING OF LUBRICANTS TO CARBON OVERCOAT OF MAGNETIC RECORDING MEDIA WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2026-05-28 US claimed
EP-4570842-A1 SELF-CLEANING TWO-COMPONENT (2K) COATING Evonik Operations GmbH (DE) 2025-06-18 EP claimed
CN-108290831-B Method for producing isocyanates 科思创德国股份有限公司 2021-11-19 CN claimed
US-20210233618-A1 SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR PREDICTING PROPERTIES OF A POLYMER COVESTRO LLC 2021-07-29 US claimed
EP-3383840-B1 METHOD FOR MAKING ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-06-02 EP claimed
US-10435353-B2 Method for producing isocyanates COVESTRO DEUTSCHLAND AG (DE) 2019-10-08 US claimed
US-20180370907-A1 METHOD FOR PRODUCING ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2018-12-27 US claimed
US-4888389-A POLYOLEFIN-POLYETHER COPOLYMERS COUPLED BY POLYISOCYANATES AND CONTAINING BOTH HYDROPHILIC AND HYDROPHOBIC GROUPS UNIVERSITY OF AKRON (US) 1989-12-19 US claimed
US-20260148750-A1 THERMO-MECHANICAL-OPTICAL BONDING OF LUBRICANTS TO CARBON OVERCOAT OF MAGNETIC RECORDING MEDIA WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2026-05-28 US disclosed
EP-4570842-A1 SELF-CLEANING TWO-COMPONENT (2K) COATING Evonik Operations GmbH (DE) 2025-06-18 EP disclosed
CN-119497543-A Apparatus and method for manufacturing display device 三星显示有限公司 2025-02-21 CN disclosed
US-20250063933-A1 APPARATUS AND METHOD FOR MANUFACTURING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2025-02-20 US disclosed
US-20240387006-A1 SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR PREDICTING PROPERTIES OF A POLYMER COVESTRO LLC 2024-11-21 US disclosed
EP-4444779-A1 BLOCKED PREPOLYMER COMPOSITIONS WITH IMPROVED STORAGE STABILITY Dow Global Technologies LLC (US) 2024-10-16 EP disclosed
US-20210233618-A1 SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR PREDICTING PROPERTIES OF A POLYMER COVESTRO LLC 2021-07-29 US disclosed
CN-112513991-A Systems, methods, and computer program products for predicting polymer properties 科思创有限公司 2021-03-16 CN disclosed
US-10435353-B2 Method for producing isocyanates COVESTRO DEUTSCHLAND AG (DE) 2019-10-08 US disclosed
US-20180370907-A1 METHOD FOR PRODUCING ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2018-12-27 US disclosed
US-20160151738-A1 CROSS-LINKED POLYIMIDE GAS SEPARATION MEMBRANE, METHOD OF MANUFACTURING THE SAME, AND USE OF THE SAME AMERICAN AIR LIQUIDE, INC. 2016-06-02 US disclosed
US-5492756-A LOW DENSITY PANELS FOR SOUND ABSORPTION, HEAT INSULATION; HAVING CURED BINDER MISSISSIPPI STATE UNIVERSITY (US) 1996-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260148750-A1 THERMO-MECHANICAL-OPTICAL BONDING OF LUBRICANTS TO CARBON OVERCOAT OF MAGNETIC RECORDING MEDIA HEATR1, HTR3D, HEATR6 CALM1 689/4885CYP3A4 4279/4885TSHR 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.