Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939002 | 0.81 | CA4 (0.47) | MAPTLTA4HALDH1A1CA4 | |
| SCHEMBL8939021 | 0.80 | CA4 (0.43) | LTA4HCA4 | |
| SCHEMBL8939010 | 0.79 | CA1 (0.48) | L3MBTL1TDP1MAPTMAPK1LTA4H | |
| SCHEMBL11506132 | 0.72 | SMN1; SMN2 (0.38) | TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8939007 | 0.72 | MAPT (0.38) | L3MBTL1TDP1ATMMAPTHPGD | |
| SCHEMBL8939008 | 0.72 | L3MBTL1 (0.38) | L3MBTL1TDP1ATMMAPTHPGD | |
| SCHEMBL3922521 | 0.71 | SCN4A (0.42) | L3MBTL1TDP1MAPTMAPK1LMNA | |
| SCHEMBL8939035 | 0.71 | SCN4A (0.37) | L3MBTL1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL27699374 | 0.71 | TSHR (0.37) | L3MBTL1TDP1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8939016 | 0.70 | DRD2 (0.36) | L3MBTL1MAPTLMNASMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |