Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939051 | 0.89 | LTA4H (0.39) | LTA4HLMNATSHRRELAL3MBTL1 | |
| SCHEMBL8939021 | 0.86 | CA4 (0.43) | DRD2DRD4DRD3LTA4HHTT | |
| SCHEMBL28876309 | 0.85 | LMNA (0.42) | DRD2DRD4DRD3SMN1; SMN2HTT | |
| SCHEMBL8939047 | 0.85 | SCN4A (0.35) | DRD2DRD4DRD3LTA4HMEN1 | |
| SCHEMBL8939014 | 0.82 | ACHE (0.42) | DRD2DRD4HTTLMNAALDH1A1 | |
| SCHEMBL8939002 | 0.81 | CA4 (0.47) | DRD2DRD4DRD3LTA4HHTT | |
| SCHEMBL27680406 | 0.80 | ACHE (0.41) | DRD2DRD4DRD3LTA4HSMN1; SMN2 | |
| SCHEMBL8939022 | 0.80 | DRD2 (0.37) | DRD2DRD4DRD3LTA4HSMN1; SMN2 | |
| SCHEMBL911476 | 0.79 | CYP3A4 (0.39) | LTA4HALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL20710810 | 0.79 | LTA4H (0.41) | DRD2DRD4DRD3TRPM8LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |