Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939008 | 0.88 | L3MBTL1 (0.38) | MAPTL3MBTL1RAB9AATMTSHR | |
| SCHEMBL8939005 | 0.80 | MAPT (0.35) | MAPTL3MBTL1ATMPOLBMEN1 | |
| SCHEMBL8939016 | 0.78 | DRD2 (0.36) | MAPTL3MBTL1RAB9ATSHRMEN1 | |
| SCHEMBL8939014 | 0.77 | ACHE (0.42) | MAPTL3MBTL1POLBTDP1HPGD | |
| SCHEMBL8939035 | 0.76 | SCN4A (0.37) | MAPTL3MBTL1TSHRCYP2C9HPGD | |
| SCHEMBL911476 | 0.74 | CYP3A4 (0.39) | L3MBTL1TSHRTDP1MEN1KMT2A | |
| SCHEMBL4433002 | 0.74 | L3MBTL1 (0.39) | MAPTL3MBTL1RAB9ATSHRHPGD | |
| SCHEMBL8939051 | 0.73 | LTA4H (0.39) | L3MBTL1TSHRPOLBTDP1LMNA | |
| SCHEMBL28018587 | 0.72 | CYP3A4 (0.38) | L3MBTL1TSHRTDP1MEN1KMT2A | |
| SCHEMBL8938985 | 0.72 | L3MBTL1 (0.43) | MAPTL3MBTL1ATMPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |