Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416448 | 0.81 | NFKB1 (0.35) | NR3C1ARPGRNR3C2NFKB1 | |
| SCHEMBL9623669 | 0.80 | NFKB1 (0.56) | NR3C1ARPGRNR3C2NFKB1 | |
| SCHEMBL9623854 | 0.79 | NFKB1 (0.33) | NR3C1NFKB1NFKB2RELAKCNH2 | |
| SCHEMBL8939564 | 0.78 | NR3C1 (0.40) | NR3C1ARPGRNR3C2ABCB11 | |
| SCHEMBL9623846 | 0.76 | NFKB1 (0.42) | NR3C1ARPGRNR3C2NFKB1 | |
| SCHEMBL9623805 | 0.71 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP17A1 | |
| SCHEMBL8940232 | 0.71 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP17A1 | |
| SCHEMBL10413147 | 0.71 | NFKB1 (0.55) | NR3C1ARPGRNR3C2NFKB1 | |
| SCHEMBL8859660 | 0.70 | NFKB1 (0.56) | NR3C1ARPGRNR3C2NFKB1 | |
| SCHEMBL10625546 | 0.70 | NFKB1 (0.56) | NR3C1ARPGRNR3C2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |