Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059388 | 0.88 | ENPP3 (0.39) | FABP3FABP4FABP5KMT2AENPP3 | |
| SCHEMBL8941429 | 0.76 | HSP90AA1 (0.44) | FABP3FABP4FABP5KMT2AENPP3 | |
| SCHEMBL11888501 | 0.68 | FABP4 (0.55) | FABP3FABP4FABP5HDAC1ENPP3 | |
| SCHEMBL8941378 | 0.67 | SMN1; SMN2 (0.50) | KMT2AENPP3ENPP1MEN1SMN1; SMN2 | |
| SCHEMBL8941153 | 0.65 | SOAT2 (0.38) | FABP3FABP4FABP5KMT2AMEN1 | |
| SCHEMBL9059244 | 0.65 | FABP3 (0.40) | FABP3FABP4FABP5ENPP3ENPP1 | |
| SCHEMBL17639907 | 0.63 | FABP4 (0.57) | FABP3FABP4FABP5HDAC1ENPP3 | |
| SCHEMBL9059390 | 0.63 | SOAT2 (0.36) | KMT2AMEN1PSMB5MAPT | |
| SCHEMBL15082948 | 0.62 | FABP4 (0.51) | FABP3FABP4FABP5HDAC1ENPP3 | |
| SCHEMBL2946584 | 0.61 | FABP4 (0.62) | FABP3FABP4FABP5HDAC1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |