Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941571 | 0.86 | ALOX5 (0.47) | ALOX5CYP1A2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8941420 | 0.84 | MIF (0.38) | ALOX5MIFCYP1A2LMNA | |
| SCHEMBL8941576 | 0.83 | ALOX5 (0.48) | ALOX5MIFCYP1A2LMNASMN1; SMN2 | |
| SCHEMBL8941751 | 0.83 | ALOX5 (0.53) | ALOX5CYP1A2LMNAGAAALDH1A1 | |
| SCHEMBL8941438 | 0.81 | POLB (0.50) | CYP1A2LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29846544 | 0.76 | F10 (0.57) | F10MIFCYP1A2LMNAGAA | |
| SCHEMBL24518326 | 0.71 | POLB (0.61) | F10ACHEMIFCYP1A2LMNA | |
| SCHEMBL25401731 | 0.67 | MIF (0.51) | F10MIFCYP1A2LMNASMN1; SMN2 | |
| SCHEMBL24517979 | 0.67 | F10 (0.43) | F10ACHEMIFCYP1A2ALDH1A1 | |
| SCHEMBL11370603 | 0.67 | SLC6A2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |