Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941438 | 0.88 | POLB (0.50) | POLBNPC1RAB9AAPAF1GRK2 | |
| SCHEMBL8941571 | 0.88 | ALOX5 (0.47) | ALOX5POLBNPC1RAB9ACA1 | |
| SCHEMBL8941414 | 0.84 | F10 (0.42) | MIFALOX5LMNACYP1A2 | |
| SCHEMBL8941576 | 0.83 | ALOX5 (0.48) | MIFALOX5POLBNPC1RAB9A | |
| SCHEMBL8941751 | 0.76 | ALOX5 (0.53) | ALOX5NPC1RAB9AHPGDLMNA | |
| SCHEMBL12556075 | 0.67 | MIF (0.56) | MIFPOLBAPAF1GRK2APOBEC3G | |
| SCHEMBL12518906 | 0.67 | MIF (0.55) | MIF | |
| SCHEMBL8941462 | 0.66 | PPARG (0.44) | ALOX5POLBNPC1RAB9AAPAF1 | |
| SCHEMBL21066127 | 0.66 | NPC1 (0.49) | NPC1RAB9ACA1CA2HPGD | |
| SCHEMBL12747543 | 0.64 | MIF (0.61) | MIFPOLBNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |