Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941751 | 0.91 | ALOX5 (0.53) | ALOX5LMNASMN1; SMN2TSHRNPC1 | |
| SCHEMBL8941571 | 0.90 | ALOX5 (0.47) | ALOX5LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8941399 | 0.87 | CA1 (0.56) | ALOX5LMNASMN1; SMN2MEN1TSHR | |
| SCHEMBL8941414 | 0.83 | F10 (0.42) | ALOX5LMNASMN1; SMN2MIFCYP1A2 | |
| SCHEMBL8941438 | 0.83 | POLB (0.50) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL8941420 | 0.83 | MIF (0.38) | ALOX5LMNANPC1RAB9AHPGD | |
| SCHEMBL8941440 | 0.80 | HTT (0.47) | ALOX5NPC1POLBMIF | |
| SCHEMBL3981403 | 0.76 | LMNA (0.56) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL10388931 | 0.72 | POLB (0.65) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL9380387 | 0.70 | ALOX5 (0.80) | ALOX5LMNAMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |